from random import choice
options = {'r': 'rock', 'p': 'paper', 's': 'scissors'}
beats = {'r': 's', 'p': 'r', 's': 'p'}
print()
print('Rock-Paper-Stone Game with computer (Ctrl+C to exit)')
print()
while True:
c_choice = choice(list(options.keys()))
p_choice = input('Enter your choice ([R]ock, [P]aper, [S]cissors): ').lower()
if p_choice not in options:
print(p_choice.upper(), 'is not a valid option.')
continue
print('You chose', options[p_choice].upper())
print('Computer chose', options[c_choice].upper())
if p_choice == c_choice:
print('It\'s a draw.')
elif beats[p_choice] == c_choice:
print('You win!')
else:
print('Computer wins!')
Source code of Rock-Paper-Scissors (r-p-s.py).